Baliao acupoint embedding for senile functional constipation: a randomized controlled study
-
摘要: [目的]比较八髎穴埋线疗法和乳果糖口服疗法治疗老年功能性便秘的临床疗效。[方法]将60例患者随机分为埋线组和乳果糖组,每组30例。埋线组予八髎穴埋线治疗,每周1次;乳果糖组予乳果糖口服液口服,每日2次,治疗8周。主要疗效指标为每周自发完全排便(spontaneous complete bowel movements,SCBM)≥ 3次的患者比例;比较治疗前后及随访第12周的疗效,包括周平均SCBM、患者生存质量评分(PAC-QOL)、Bristol大便性状积分和排便困难程度评分。[结果]治疗后埋线组每周SCBM ≥ 3次的患者比例与乳果糖组比较差异有统计学意义(P<0.01);与本组治疗前比较,埋线组和乳果糖组患者治疗后周平均SCBM次数增加(均P<0.05),大便性状积分改善(均P<0.01),PAC-QOL评分和排便困难程度评分均降低(均P<0.01);治疗8周后埋线组周平均SCBM次数明显多于乳果糖组(P<0.01),PAC-QOL量表评分、Bristol大便性状和排便困难程度改善均优于乳果糖组(P<0.05);随访12周埋线组周平均SCBM次数多于乳果糖组(P<0.01)。[结论]八髎穴埋线可以明显增加老年功能性便秘患者的SCBM,改善Bristol大便性状和排便困难程度,提高其生活质量。Abstract: [Objective] To compare the effects between acupoint embedding and oral medication for senile functional constipation.[Methods] Sixty senile patients were randomized into an embedding group and a medication group(1[BFZ]:1).Baliao acupoint embedding in the embedding group, it was given once a week.Oral lactulose was applied in the lactulose group, 2 times a day.The treatment cycle was 8 weeks.The primary outcome was The Proportion of patients per week more than 3 times spontaneous complete bowel movements(SCBM).The secondary efficacy indices were compared before and after treatment as well as at follow-up at the 12 th week, the weekly average number of SCBM, the quality of life of patients with constipation(PAC-QOL), the Bristol stool character score, and the assessment of difficulty in defecation.[Results] After treatment, the patients whose weekly Proportion of SCBM ≥ 3 times in the embedding group was have statistically significant compared with that in the lactulose group(P<0.01);The weekly average number of SCBM in the two groups increased after treatment compared with those before treatment(both P<0.05);the score of Bristol stool character improved(both P<0.01);the scores of PAC-QOL and difficulty in defecation decreased(all P<0.01);After 8 weeks of follow-up, the number of SCBM in the catgut embedding group was more than that in the lactulose group(P<0.01), the score of PAC-QOL in the embedding group after treatment was better than that in the medication group(P<0.05);the Bristol stool character and difficulty degree in the embedding group after treatment were superior to those in the medication group(both P<0.05);After 12 weeks of follow-up, the number of SCBM in the catgut embedding group was more than that in the lactulose group(P<0.01).[Conclusion] The acupoint embedding significantly improve the SCMB, Bristol stool character, the difficulty of defecation, and the quality of life for senile patients with functional constipation.
-
-
[1] 于普林, 李增金, 郑宏, 等.老年人便秘流行病学特点的初步分析[J].中华老年医学杂志, 2001, 20(2):132-134.
[2] 杨龙明.老年性便秘的诊疗[J].中国医药指南, 2012, 10(21):372-373.
[3] Liu Z, Liu J, Zhao Y, et al.The efficacy and safety study of electro-acupuncture for severe chronic functional constipation:study protocol for a multicenter, randomized, controlled trial[J].Trials, 2013, 14(1):176-176.
[4] Zhang T, Chon T Y, Liu B, et al.Efficacy of acupuncture for chronic constipation:a systematic review[J].Am J Chin Med, 2013, 41(4):717-742.
[5] Lin L W, Fu Y T, Dunning T, et al.Efficacy of traditional Chinese medicine for the management of constipation:a systematic review[J].J Altern Comp Med, 2009, 15(12):1335-1346.
[6] Wedel T, Spiegler J, Soellner S, et al.Enteric Nerves and Interstitial Cells of Cajal Are Altered in Patients with Slow-Transit Constipation and Megacolon[J].Gastroenterology, 2002, 123(5):1459-1467.
[7] 洪霞, 蒋勍, 汤晓琴, 等.穴位埋线联合生物反馈治疗功能性便秘的临床研究[J].中华全科医学, 2018, 16(2):218-221.
[8] 侯毅, 谷云飞, 朱秉宜.普芦卡必利治疗慢性便秘的系统评价[J].世界华人消化杂志, 2014, 22(4):588-595.
[9] Patrick M, Christine D L L, Dominique D, et al.Development and validation of the Patient Assessment of Constipation Quality of Life questionnaire[J].Sca J Gastroenterol, 2005, 40(5):540-551.
[10] Tack J, Talley N J.Functional dyspepsia-symptoms, definitions and validity of the Rome III criteria[J].Nat Rev Gastroenterol Hepatol, 2013, 10(3):134-141.
[11] 曲牟文, 李国栋, 洪子夫, 等.八髎穴埋线治疗慢传输型便秘30例临床观察[J].中医杂志, 2013, 54(19):1663-1665.
[12] 陈利芳, 金晓飞, 蒋旭, 等.简易穴位埋线法治疗女性功能性便秘:随机对照研究[J].中国针灸, 2017, 37(7):717-721.
[13] 郑筱萸.中药新药临床研究指导原则(试行)[M].北京:中国医药科技出版社, 2002:134-137.
[14] 李军祥, 陈誩, 柯晓.功能性便秘中西医结合诊疗共识意见(2017年)[J].中国中西医结合消化杂志, 2018, 26(1):18-26.
[15] 张一辉, 杨建华.理气开秘法治疗功能性便秘的临床观察[J].光明中医, 2018, 33(4):501-503.
[16] Holzer B, Rosen H, Novi G, et al.Sacral nerve stimulation in patients with severe constipation[J].Dis Col Rec, 2008, 51(5):524-529.
[17] 陆忠.点刺四缝、八髎穴治疗食积内热型小儿功能性便秘48例[J].中国针灸, 2018, 38(4):362-363.
[18] 邹洋洋, 丁曙晴, 周惠芬, 等.八髎穴治疗出口梗阻型便秘的机制探讨[J].针灸研究, 2015, 40(5):427-430.
[19] 贾菲, 李国栋.电针八髎穴及承山穴治疗慢传输型便秘疗效观察[J].现代中西医结合杂志, 2015, 24(10):1055-1057.
[20] 王玲玲, 金洵.重新认识八髎穴[J].南京中医药大学学报, 2014, 30(1):4-7.
[21] 孙明明, 丁曙晴, 丁义江.慢性功能性便秘的针灸治疗进展[J].结直肠肛门外科, 2007, 13(3):192-194.
[22] 张选平, 贾春生, 王建岭, 等.穴位埋线疗法的优势病种及应用规律[J].中国针灸, 2012, 32(10):947-951.
[23] 李东冰, 李权, 吴丹明, 等.穴位埋线治疗慢传输型便秘的临床研究[J].中国针灸, 2004, 24(9):600-602.
[24] 薛雏华, 马彦平, 高秀领.穴位埋线配合走罐治疗习惯性便秘58例[J].中国针灸, 2010, 30(9):720-720.
[25] 彭如洁, 曾庆新.益生菌联合乳果糖治疗老年人功能性便秘临床研究[J].现代医药卫生, 2018, 34(4):576-578.
-
计量
- 文章访问数: 1192
- PDF下载数: 1335
- 施引文献: 0

下载: