活动期溃疡性结肠炎患者血脂与蛋白质变化

刘通; 张飞越; 高攀; 费素娟

doi:10.3969/j.issn.1671-038X.2018.09.10

活动期溃疡性结肠炎患者血脂与蛋白质变化

- 1. 徐州医科大学, 江苏徐州 221002;
- 2. 徐州医科大学附属医院消化内科, 江苏徐州 221006

详细信息

作者简介:
刘通,硕士在读

通讯作者: 费素娟,E-mail:xyfyfeisj99@163.com

中图分类号: R574.6

收稿日期: 2018-06-10

Serum lipids and protein changes in patients with ulcerative colitis

- 1. Xuzhou Medical University, Jiangsu, Xuzhou 221002, China;
- 2. Department of Gastroenterology, the Affiliated Hospital of Xuzhou Medical University, Jiangsu, Xuzhou 221006, China

More Information

Corresponding author: FEI Su-juan, E-mail: xyfyfeisj99@163.com

Received Date: 10 June 2018

摘要

摘要: [目的]观察活动期溃疡性结肠炎（UC）患者血脂与蛋白质水平，评价其与病情严重程度间的关系。[方法]对活动期UC住院患者94例与体检正常者（对照组）100例的总胆固醇（TC）、甘油三酯（TG）、低密度脂蛋白（LDL）、高密度脂蛋白（HDL）、总蛋白（TP）、白蛋白（ALB）、前白蛋白（PA）水平进行回顾并研究其与严重程度之间的关系。[结果]与对照组比较，活动期UC患者TC、TG、LDL、HDL、TP、ALB、PA水平明显降低，TC、TP、ALB水平与Baron评分呈负相关，ALB与ESR负相关。[结论]活动期UC患者易出现血脂及蛋白异常，TC、ALB可作为病情严重程度评价指标。
- 溃疡性结肠炎 /
- 血脂 /
- 蛋白质
Abstract: [Objective] To observe the relationship between serum lipid and protein levels and the severity of patients with ulcerative colitis(UC).[Methods] Ninety-four UC patients and 100 healthy people were enrolled.Total cholesterol(TC), triglyceride(TG), low-density lipoprotein(LDL), high-density lipoprotein(HDL), total protein(TP), albumin(ALB), prealbumin(PA) were reviewed, and their correlations with the severity were analyzed.[Results] TC, TG, LDL, HDL, TP, ALB, PA in active UC patients were significantly lower than those in controls(P<0.05).Correlation analysis showed that TC, TP, ALB was correlated with the Baron score(P<0.05).ALB was correlated with ESR(P<0.05).[Conclusion] Disorder of lipid and protein occur in active UC patients.ALB can be used as an evaluation indicator for the disease severity.
- ulcerative colitis /
- serum lipids /
- protein

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