Clinical observation on treatment of functional dyspepsia with Tiaozhonghuashi decoction
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摘要: [目的]探讨调中化湿汤治疗功能性消化不良(脾虚气滞证)的临床疗效及对患者抑郁焦虑状态的影响。[方法]选取我院脾胃病科门诊2017年1月~2017年12月诊治的100例功能性消化不良患者作为观察对象,根据患者的就诊单双号随机分为观察组和对照组各50例,2组患者均给予枸橼酸莫沙必利片治疗,观察组在对照组的基础上加用调中化湿汤治疗,2组疗程均为4周,对比2组疗效差异。[结果]4周疗程结束后观察组中医症候积分及SAS、SDS评分低于对照组(P<0.05);观察组愈显率显著高于对照组(P<0.05);3个月随访复发率观察组低于对照组(P<0.05)。[结论]在西医常用药物莫沙必利片治疗基础上加用调中化湿汤治疗功能性消化不良(脾虚气滞证)患者能进一步提高临床疗效,改善患者消化不良症状及焦虑、抑郁症状,且远期疗效稳定。Abstract: [Objective] To explore the clinical efficacy of Tiaozhonghuashi Decoction in treating functional dyspepsia (deficiency of spleen deficiency and qi stagnation) and its effect on depression and anxiety in patients. [Methods] 100 patients were selected with functional dyspepsia (splenic qi stagnation syndrome) who were diagnosed and treated in the spleen and gastroenterology department of the First Affiliated Hospital of Guangxi Traditional Medicine University from January 2017 to December 2017. According to the single and double number of patients, they were randomly divided into observation group and control group (50 cases for each group). Both groups of patients were given mosapride citrate tablets, while the observation group was treated with Tiaozhonghuashi Decoction as additional regimen. The course of treatment in both groups was 4 weeks, and differences in efficacy between the two groups were observed.[Results] After 4 weeks of treatment, TCM symptoms scores, SAS and SDS scores were all lower in the observation group than in the control group (P<0.05). The observed efficiency rate in the observation group was significantly higher than that in the control group (P<0.05); the recurrence rate at the 3 months follow-up was lower in the observation group than in the control group (P<0.05). [Conclusion] The additional Tiaozhonghuashi Decoction treatment on the basis of the western medical treatment of mosapride tablets commonly clinically used can increase the clinical efficacy and improve the symptoms of dyspepsia, anxiety and depressive symptoms of patients with functional dyspepsia (spleen deficiency and qi stagnation), and the long-term curative effect is stable.
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Key words:
- Tiaozhonghuashi decoction /
- functional dyspepsia /
- clinical observation
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