武汉地区汉族健康人群ABO、RhD血型分布调查

徐朴; 熊艳; 曹奎杰

doi:10.13201/j.issn.1004-2806-b.2015.10.003

武汉地区汉族健康人群ABO、RhD血型分布调查

- 1. 武汉大学人民医院输血科;
- 2. 华中科技大学同济医学院附属协和医院检验科;
- 3. 华中科技大学同济医学院附属协和医院输血科

详细信息

通讯作者: 曹奎杰,E-mail:ckj369@126.com

中图分类号: R457.1

收稿日期: 2014-09-22

Distribution of ABO and RhD blood group among Healthy Han population in Wuhan

- 1. Department of Blood Transfusion,Renmin Hospital of Wuhan University;
- 2. Department of Clinical Laboratory,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology;
- 3. Department of Blood Transfusion,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology

More Information

Corresponding author: CAO Kuijie, E-mail: ckj369@126.com

Received Date: 22 September 2014

摘要

摘要: 目的:调查武汉地区汉族健康人群ABO血型及RhD血型分布特征。方法:应用强生Auto/Vue全自动血型分析仪检测3 694名武汉地区汉族健康体检者ABO和Rh血型,并随机与其他地区汉族人群ABO血型分布相比较。结果:武汉地区汉族健康体检人群ABO血型分布特征为(O>A>B>AB),A、B、O 的基因频率p、q、r 分别为0.233 6、0.187 6和0.581 7 (r>p>q)。该人群中不同年龄组及不同性别间ABO 血型分布差异无统计学意义(P>0.05), 但和豫西南、贵州毕节地区汉族人群ABO 血型分布比较差异有统计学意义(P<0.05);RhD阴性分布频率为0.38%。结论:武汉地区汉族健康人群O型频率具有典型的南方人群ABO 血型分布特征;不同地域间汉族人群ABO 血型分布不同;武汉地区汉族健康人群RhD阴性频率极低。
- ABO血型 /
- RhD血型 /
- 基因频率 /
- 汉族 /
- 武汉
Abstract: Objective:To investigate the distribution of ABO and RhD blood groups among Han population in Wuhan, Hubei province. Method:A total of 3 694 Han healthy individuals were identified by AutoVue immunohaematology analyser and the distribution of blood groups was compared randomly with others 2 Han populations.Result:Among Han population in Wuhan, the distribution feature of ABO blood groups was O>A>B>AB and the p, q and r values of gene frequency of A, B, O were 0.233 6, 0.187 6 and 0.581 7 (r>p>q) respectively. The distribution of ABO blood group was not significantly different in different age and sex groups (P>0.05), but it was significantly different when compared with those of others 2 Han populations(P<0.05). The frequency of negative RhD was 0.38%.Conclusion:The distribution feature of O gene frequency among Han population in Wuhan was similar to those among southern Han population. The distribution of Han population ABO blood group among different area was significantly different. The frequency of negative RhD was very low in this study.
- ABO blood group /
- RhD blood group /
- gene frequency /
- Han population /
- Wuhan

HTML全文

参考文献(8)

[1]	王爱梅,丁玉琴,马凤巧. 豫西南地区汉族人群ABO血型及Rh血型分布调查[J]. 实用预防医学,2005,12(3):581-582.
[2]	江家志,龙友国,龙思方.瓮安汉族人群ABO血型分布调查[J].现代预防医学,2009,36(14):2604-2605.
[3]	陈显智.毕节地区ABO血型、Rh血型人群分布情况调查[J].卫生职业教育,2010,28(10):101-102.
[4]	赵桐茂.人类血型遗传学[M].北京:科学技术出版社,1987:47-228.
[5]	Vivek S, Jain J, Simon SP, et al. Association of ABO Blood Group and Rh factor with Periodontal Disease in a Population of Virajpet, Karnataka:A Cross-Sectional Study[J]. J Int Oral Health, 2013,5:30-34.
[6]	Fang C, Cohen HW, Billett HH. Race, ABO blood group, and venous thromboembolism risk:not black and white[J].Transfusion,2013, 53:187-192.
[7]	Ségurel L, Gao Z, Przeworski M. Ancestry runs deeper than blood:the evolutionary history of ABO points to cryptic variation of functional importance[J]. Bioessays,2013,35:862-867.
[8]	陈稚勇,赵桐茂,张工梁.中国人ABO血型分布[J]. 遗传,1982, 4(2):4-7.